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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I Finally Have My ANA Test Results. What Does All This Mean?

A myPBCteam Member asked a question 💭
Panama City Beach, FL
August 14
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A myPBCteam Member

Antinuclear antibodies (ANAs) are antibodies that target the nucleus of cells. In the context of Primary Biliary Cholangitis (PBC):

- Presence of ANAs: Around half of people with PBC have ANAs. They are more common in those who don’t have antimitochondrial antibodies (AMAs)
- Specificity: ANAs are less specific for PBC Show Full Answer

Antinuclear antibodies (ANAs) are antibodies that target the nucleus of cells. In the context of Primary Biliary Cholangitis (PBC):

- Presence of ANAs: Around half of people with PBC have ANAs. They are more common in those who don’t have antimitochondrial antibodies (AMAs).
- Specificity: ANAs are less specific for PBC because they can be found in other autoimmune diseases like lupus and rheumatoid arthritis.
- Diagnosis: While ANAs can support a PBC diagnosis, they are not the only factor. Other tests and clinical evaluations are necessary.

For a detailed understanding of your specific case, it's best to discuss your results with your doctor.

August 14

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