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Real members of myPBCteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I Am Interested In Learning More About Seladelpar Which Has Been Recently Approved And Has Shown To Lower ALP Numbers. Has Anyone Tried It?

A myPBCteam Member asked a question 💭
Peniel, FL
October 24
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A myPBCteam Member

Thank-you for letting me know what you learned. I was hoping the manufacturer's program would be more helpful to everyone due to the extremely high cost of their product.

November 5
A myPBCteam Member

Seladelpar, also known by its brand name Livdelzi, is approved by the U.S. Food and Drug Administration (FDA) for treating primary biliary cholangitis (PBC) in adults. It is prescribed in combination with ursodeoxycholic acid (UDCA) for those who do not respond adequately to UDCA alone or as a monotherapy for those who Show Full Answer

Seladelpar, also known by its brand name Livdelzi, is approved by the U.S. Food and Drug Administration (FDA) for treating primary biliary cholangitis (PBC) in adults. It is prescribed in combination with ursodeoxycholic acid (UDCA) for those who do not respond adequately to UDCA alone or as a monotherapy for those who cannot tolerate UDCA.

Key Points About Seladelpar (Livdelzi):
- Mechanism: It is a peroxisome proliferator-activated receptor (PPAR)-delta agonist, believed to work by reducing alkaline phosphatase (ALP) levels.
- Administration: Taken orally as a capsule once daily, with or without food.
- Common Side Effects: Headache, abdominal pain, nausea, abdominal distension (bloating), and dizziness.
- Serious Side Effects: Fractures, liver test abnormalities, and biliary obstruction.

For more detailed experiences and discussions, you might want to visit the myPBCteam website where individuals share their experiences with treatments like Livdelzi.

October 24
A myPBCteam Member

Yes I could only find where they would offer assistance to the one without insurance and for those with insurance they offer a coupon program for up to $10k per year (monthly cost of medication is over $12k per month)

November 4
A myPBCteam Member

Did your doctor give you the manufacturer's website information to apply for their assistance program?

November 4
A myPBCteam Member

My doctor prescribed this but so far my insurance has denied it.

November 4

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