Antihistamines for PBC

Overview
Antihistamines are a class of drugs used to treat allergy symptoms, and they are often prescribed to help with itching associated with primary biliary cholangitis. Antihistamines are believed to work by reducing or blocking histamines, which can help stop the itching sensation. Diphenhydramine, hydroxyzine hydrochloride, and loratadine are examples of antihistamines used to reduce itching. Feeling less itchy can also help improve sleep.

How do I take it?
Depending on the situation, antihistamines are available as tablets, capsules, liquids, syrups, creams, lotions, gels, eye drops, and nasal sprays. Your doctor can advise you on the best formula and dose for your symptoms.

Side effects
Common side effects of antihistamines include drowsiness, dry mouth, dry eyes, blurred or double vision, dizziness, headache, low blood pressure, mucous thickening in the airways, rapid heart rate, difficulty urinating, and constipation.

Check the information that comes with your medication for a full list of possible side effects and advice about when to seek medical help.

For more details about this treatment, visit:

Primary Biliary Cholangitis — Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/...

Antihistamines — Cleveland Clinic
https://my.clevelandclinic.org/health/drugs/212...